| soutěžcompetitionNoun | Noun |
| soutěžitto competeVerb | Verb |
| sovaowlNoun | Noun |
| spadnoutto fall downVerb | Verb |
| spáchatto commitVerb | Verb |
| spálit seto burn oneself, to get burnedVerb | Verb |
| spáneksleepNoun | Noun |
| spátto sleepVerb | Verb |
| specialistaspecialistNoun | Noun |
| specialitaspecialtyNoun | Noun |
| speciálníspecialAdjective | Adjective |
| spěchatto hurry, to rushVerb | Verb |
| spěšnýurgent; expressAdjective | Adjective |
| spínací špendlíksafety pinPhrase | Phrase |
| spisovatelwriterNoun | Noun |
| spisovatelkafemale writerNoun | Noun |
| spíšrather, moreParticle | Particle |
| spíšerather, moreParticle | Particle |
| splátkainstalmentNoun | Noun |
| splést semake a mistakePhrase | Phrase |
| spočítatto count, to calculateVerb | Verb |
| spodnílower; bottomAdjective | Adjective |
| spodní prádlounderwearWord combination | Word combination |
| spojeníconnectionNoun | Noun |
| spokojenýsatisfiedAdjective | Adjective |
| spokojený ssatisfied withGrammar pattern | Grammar pattern |
| společnětogether; jointlyAdverb | Adverb |
| společnostcompany, societyNoun | Noun |
| společnost s ručením omezenýmlimited liability companyWord combination | Word combination |
| společnýshared; commonAdjective | Adjective |
| spolehlivýreliableAdjective | Adjective |
| spolutogetherAdverb | Adverb |
| spolubydlícíflatmateNoun | Noun |
| spoluprácecooperationNoun | Noun |
| spolužákclassmateNoun | Noun |
| spontánnostspontaneityNoun | Noun |
| sponzorsponsorNoun | Noun |
| sporákstoveNoun | Noun |
| sportsportNoun | Noun |
| sportovatto play sports, to exerciseVerb | Verb |
| sportovecathleteNoun | Noun |
| sportovkyněfemale athleteNoun | Noun |
| sportovnísport-related; athleticAdjective | Adjective |
| sportovní potřebysports equipmentWord combination | Word combination |
| spotřebaconsumptionNoun | Noun |
| spotřebičapplianceNoun | Noun |
| spotřebníconsumer; consumption-relatedAdjective | Adjective |
| spoustaa lotNoun | Noun |
| správněcorrectlyAdverb | Adverb |
| správnýright; correctAdjective | Adjective |
| sprchashowerNoun | Noun |
| sprchovat seto showerVerb | Verb |
| sprchovýshower-relatedAdjective | Adjective |
| sprchový koutshower cubicleWord combination | Word combination |
| spropitnétip, gratuityNoun | Noun |
| sprostývulgar; rudeAdjective | Adjective |
| SPZspzlicence plateWord combination | Word combination |
| squashsquashNoun | Noun |
| srazmeeting, meetupNoun | Noun |
| srazit seto collideVerb | Verb |
| srážkacollision; precipitationNoun | Noun |
| srdceheartNoun | Noun |
| srdečněwarmly; cordiallyAdverb | Adverb |
| srdečně Tě zdravísrdečně tě zdravísends warm greetingsPhrase | Phrase |
| srdíčkolittle heartNoun | Noun |
| srkatto sip, to slurpVerb | Verb |
| srovnánícomparisonNoun | Noun |
| srpenAugustNoun | Noun |
| stačitto be enoughVerb | Verb |
| stadionstadiumNoun | Noun |
| stagnovatto stagnateVerb | Verb |
| stáhnoutto downloadVerb | Verb |
| stahovatto downloadVerb | Verb |
| stánekstand, stallNoun | Noun |
| stánístanding, standing roomNoun | Noun |
| stanicestationNoun | Noun |
| stanice metrametro stationWord combination | Word combination |
| stanovištěstand, stationNoun | Noun |
| stanoviště taxitaxi rankWord combination | Word combination |
| starat setake careVerb | Verb |
| starobníold-ageAdjective | Adjective |
| starostconcern, worryNoun | Noun |
| starostamayorNoun | Noun |
| starostkafemale mayorNoun | Noun |
| starýoldAdjective | Adjective |
| státstate, countryNoun | Noun |
| stát (kde)to standVerb | Verb |
| stát seto happen; becomeVerb | Verb |
| statečnýbraveAdjective | Adjective |
| statistikastatisticsNoun | Noun |
| státnístate; governmentAdjective | Adjective |
| státní občanstvícitizenshipWord combination | Word combination |
| státní příslušnostnationalityWord combination | Word combination |
| státní zastupitelstvípublic prosecutor's officeWord combination | Word combination |
| stavstate, condition, statusNoun | Noun |
| stavbaconstruction, buildingNoun | Noun |
| stavětto buildVerb | Verb |
| stážinternshipNoun | Noun |
| stážistainternNoun | Noun |
| stážistkafemale internNoun | Noun |